Bio-Rad

VARIANT II Hemoglobin Testing System

High-volume, fully automated HPLC haemoglobin analysis — the reference standard for β-thalassaemia testing and HbA1c for over 25 years.

Key Features

The Reference Standard in Haemoglobin Analysis

The Bio-Rad VARIANT II has been the method of choice at expert reference centres for over 25 years. Its fully automated HPLC platform delivers clinically accurate results for HbA1c and β-thalassaemia with minimal hands-on time.

Fully automated — no sample preparation required
Closed-tube primary sampling with barcode reading
NGSP-certified and CE marked IVD
IFCC traceable, DCCT anchored for HbA1c
CDM Software with real-time LIS data transmission
β-Thalassaemia Short Program — 25+ year gold standard
Complete ready-to-use test kits
Positive specimen identification throughout

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Test Menu

What the VARIANT II Tests

Comprehensive haemoglobin analysis for high-volume clinical and reference laboratories.

HbA1c

Gold-standard glycated haemoglobin — NGSP-certified diabetes monitoring

β-Thalassaemia Short Program

25+ year reference standard for β-thalassaemia carrier screening and diagnosis

HbA2 Quantification

Precise HbA2 measurement — elevated in β-thalassaemia trait

HbF (Foetal Haemoglobin)

Quantification for thalassaemia and HPFH diagnosis

Haemoglobin Variants

Detection of HbS, HbC, HbD, HbE and other clinically significant variants

Sickle Cell Screening

HbS quantification and sickle cell disease confirmation

Technical Specifications

VARIANT II Specifications

Method	High Performance Liquid Chromatography (HPLC)
Certification	NGSP-certified, CE marked IVD, IFCC traceable
Sample Handling	Closed-tube primary sampling, barcode reading
Chromatographic Station	53.2 × 27.2 × 40.7 cm
Sampling Station	45.5 × 61.6 × 59.6 cm
Power Supply	100–120 V / 200–240 V, 50/60 Hz, 200 VA
Data Management	CDM Software with LIS interface
Sample Type	Whole blood (EDTA)