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VARIANT™ nbs Newborn Screening System

The worldwide standard in automated newborn haemoglobin screening — identifying sickle cell disease and haemoglobinopathies from dried blood spots.

Bio-Rad VARIANT nbs Newborn Screening System

The Gold Standard in Newborn Haemoglobin Screening

The Bio-Rad VARIANT™ nbs is the established worldwide standard for automated newborn screening for sickle cell disease and other haemoglobinopathies. Using dried blood spot specimens — the same heel-prick cards used in standard newborn screening programmes — it delivers fully automated HPLC analysis with walk-away efficiency and advanced pattern reporting.

  • Worldwide standard for newborn haemoglobin screening
  • Analyses dried blood spot (DBS) specimens — no venepuncture required
  • Fully automated HPLC analysis — walk-away operation
  • 3-minute analysis time per sample
  • Up to 1,128 samples per automated run
  • Advanced "pattern" result reporting for maximum accuracy
  • Barcode reader for complete sample traceability
  • LIS interface for real-time data transmission
  • Two-module system: Chromatography Station + Automatic Sampler
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What the VARIANT™ nbs Screens

Comprehensive newborn haemoglobin screening from dried blood spot specimens.

HbF (Foetal Haemoglobin)

Primary haemoglobin in newborns; elevated patterns indicate haemoglobinopathy

HbA (Adult Haemoglobin)

Presence confirms normal adult haemoglobin expression in neonates

HbS (Sickle Cell)

Detection of sickle cell disease (HbSS) and sickle cell trait (HbAS)

HbC Detection

Identifies HbC trait and HbSC disease in newborn blood spots

HbD & HbE Variants

Screens for clinically significant HbD and HbE haemoglobin variants

β-Thalassaemia Patterns

Identifies carrier and affected newborns through characteristic HPLC patterns

VARIANT™ nbs Specifications

MethodHigh Performance Liquid Chromatography (HPLC)
Sample TypeDried blood spots (DBS) on filter paper
Analysis Time3 minutes per sample
Capacity per RunUp to 1,128 samples
System ModulesChromatography Station (VNCS) + Automatic Sampler (VNAS)
Dimensions (W × D × H)61 × 45.7 × 55.9 cm
Weight54.4 kg
Power Supply110–240 VAC, 50/60 Hz
LIS InterfaceYes — real-time data transmission

Interested in the Bio-Rad VARIANT™ nbs?

Contact QLS Jamaica to discuss newborn screening implementation for your institution.

Request a Quotation   Book a Demo