Bio-Rad
The worldwide standard in automated newborn haemoglobin screening — identifying sickle cell disease and haemoglobinopathies from dried blood spots.
Key Features
The Bio-Rad VARIANT™ nbs is the established worldwide standard for automated newborn screening for sickle cell disease and other haemoglobinopathies. Using dried blood spot specimens — the same heel-prick cards used in standard newborn screening programmes — it delivers fully automated HPLC analysis with walk-away efficiency and advanced pattern reporting.
Test Menu
Comprehensive newborn haemoglobin screening from dried blood spot specimens.
Primary haemoglobin in newborns; elevated patterns indicate haemoglobinopathy
Presence confirms normal adult haemoglobin expression in neonates
Detection of sickle cell disease (HbSS) and sickle cell trait (HbAS)
Identifies HbC trait and HbSC disease in newborn blood spots
Screens for clinically significant HbD and HbE haemoglobin variants
Identifies carrier and affected newborns through characteristic HPLC patterns
Technical Specifications
| Method | High Performance Liquid Chromatography (HPLC) |
| Sample Type | Dried blood spots (DBS) on filter paper |
| Analysis Time | 3 minutes per sample |
| Capacity per Run | Up to 1,128 samples |
| System Modules | Chromatography Station (VNCS) + Automatic Sampler (VNAS) |
| Dimensions (W × D × H) | 61 × 45.7 × 55.9 cm |
| Weight | 54.4 kg |
| Power Supply | 110–240 VAC, 50/60 Hz |
| LIS Interface | Yes — real-time data transmission |