Bio-Rad

PR 4100 Absorbance Microplate Reader

Next-generation 8-channel microplate reader — fast, accurate absorbance measurement for ELISA-based infectious disease and autoimmune diagnostics.

Key Features

Precision ELISA Reading in Under 15 Seconds

The Bio-Rad PR 4100 is a compact, next-generation 8-channel absorbance microplate reader designed for high-quality ELISA reading in clinical diagnostic laboratories. With LED-based optics, maintenance-free operation, and powerful Magellan Tracker software, the PR 4100 delivers reliable, traceable results for every plate.

8-channel simultaneous reading — full 96-well plate in under 15 seconds
Reference channel included for enhanced measurement accuracy
LED light source — long life, maintenance-free, no lamp replacement
Integrated filter wheel: 405, 450, 492, 550, 620 nm (standard filters)
Measurement range 0–4.0 OD with 0.0001 OD resolution
Magellan Tracker software — full qualitative and quantitative EIA analysis
Complete data traceability — compliant with FDA 21 CFR Part 11
Compact bench-top design: 347 × 189 × 134 mm, only 2.6 kg

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Complementary Equipment: The PR 4100 is designed to work seamlessly alongside the Bio-Rad EVOLIS™ automated EIA system, the PW 42 Microplate Washer, and the IPS Microplate Incubator for a complete ELISA workflow.

Applications

What the PR 4100 Reads

Versatile absorbance reading for the full range of EIA-based clinical diagnostic assays.

HIV 1/2 Antibody Screening

Reads EIA-based HIV screening assays — optical density interpretation for reactive/non-reactive classification

HBsAg (Hepatitis B)

Measures OD values for Hepatitis B surface antigen detection in blood donor and clinical screening

HCV Antibody Testing

ELISA-based Hepatitis C antibody detection with precise OD measurement at 450 nm

Syphilis Serology

Treponemal and non-treponemal antibody EIA plate reading for syphilis screening programmes

Autoimmune Testing

ANA, Anti-dsDNA, ENA profile and other autoimmune EIA panels read with quantitative OD analysis

HTLV I/II Screening

ELISA reading for Human T-Lymphotropic Virus antibody detection in transfusion medicine

Chagas Disease

Serological EIA screening for Trypanosoma cruzi antibodies

General EIA / ELISA Assays

Open platform — reads any microplate-based EIA assay at wavelengths 400–750 nm

Quantitative & Qualitative Analysis

Magellan Tracker software supports both cut-off ratio calculations and quantitative standard curve analysis

Technical Specifications

PR 4100 Specifications

Detection Mode	Absorbance (photometry)
Reading Channels	8 simultaneous channels + 1 reference channel
Reading Speed	< 15 seconds per wavelength (96-well plate)
Measurement Range	0–4.0 OD
Resolution	0.0001 OD
Wavelength Range	400–750 nm
Standard Filters	405, 450, 492, 550, 620 nm
Light Source	LED (maintenance-free, long life)
Software	Magellan Tracker — qualitative & quantitative EIA analysis
Regulatory Compliance	CE-IVD; FDA 21 CFR Part 11 compliant
Dimensions (W × D × H)	347 × 189 × 134 mm
Weight	2.6 kg